Spironolactone
3 Steps to Get Started
Spironolactone is a diuretic (a “water pill”), which means it is a medication that removes fluid from your body through urination.
It can also be used off-label to treat the following in women:
Spironolactone slows down your body’s production of androgen hormones, such as testosterone. These hormones can make the skin produce too much oil, which clogs pores and causes acne. These hormones are also the main culprit responsible for hair loss.
While androgen hormones promote masculine characteristics, everyone — even women — needs a certain amount of androgens for normal body functions. But lowering the hormones down from an excessive amount can help with acne and hair loss.Â
Spironolactone takes a while to start working, so don’t be discouraged if you don’t see improvement right away.
For acne
Most people start to see less breakouts and oily skin within a few weeks, but your response to the medication may be different. Studies have also found that people tend to get more of a benefit from the medication the longer they take it.
For hair Loss
Most people need to take it for at least six months before they start seeing results. Others might not notice any benefits until they’ve taken it for at least a year.
Follow up with your doctor after taking Spironolactone for six months. Depending on your results, they might increase your dosage or prescribe a different medication to take with or instead of Spironolactone.
For acne
A retrospective study evaluating Spironolactone for the treatment of acne showed that 86% of patients' acne condition improved on Spironolactone therapy.
For hair loss
In a small study involving just four patients, a 200mg dose of Spironolactone administered daily reduced hair loss by up to 62.9%.Â
Taking Spironolactone in conjunction with birth control pills may also be beneficial. Birth control helps with irregularities in your period while also improving acne and female pattern hair loss. Triple score!
For acne
To treat inflammatory acne in women, Spironolactone is prescribed at a dosage of 25mg to 200mg per day. If you’re prescribed Spironolactone to treat acne, your healthcare provider will usually suggest starting at a low dose, then gradually increasing your dose over time as required.
For hair loss
Because female pattern hair loss is an off-label indication for Spironolactone, there’s no precise, agreed-upon dosage. However, most healthcare providers prescribe spironolactone for hair loss at a dosage of 100mg to 200mg per day.
If you’re prescribed Spironolactone for hair loss, your doctor will usually instruct you to take your medication in a single dose, either in the morning or evening.
If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.
Most people do well on spironolactone, but all medications can cause side effects.
The most common side effects of spironolactone are:
Inform your healthcare professional if these side effects do not go away and become bothersome to you.
Inform your healthcare professional if:Â
Inform your healthcare professional if you are taking or intend to take any other medication, supplements, traditional medications, or herbal remedies.
The above information answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.
References
https://www.goodrx.com/spironolactone/spironolactone-for-acne-how-does-it-work
https://www.healthhub.sg/a-z/medications/289/Spironolactone
https://www.karger.com/Article/Fulltext/471799
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769411
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