Neo-Penotran

What is Neo-Penotran used for​​​?

Neo-Penotran is commonly used to treat various vaginal infections such as vaginal yeast infection (vaginal candidiasis), bacterial vaginosis (such as anaerobic vaginal infections and Gardnerella vaginalis), Trichomonas vaginalis and mixed vaginal infections. Neo-Penotran is a vaginal pessary that contains two active ingredients - an antibiotic Metronidazole (500mg) and an antifungal Miconazole (100mg).

Dosage and How to Use​

Neo-Penotran is meant strictly for vaginal use. Your doctor may prescribe you one of the following regimens for your infection:

1. Insert one Neo-Penotran pessary deep into the vagina in the evening for 14 days or

2. Insert one Neo-Penotran pessary in the morning and one in the evening for 7 days.

In the case of recurrent vaginitis, option one (14 days regimen) should be used.

Neo-Penotran should be inserted deep into the vagina while in the lying position, and should not be used during the menstrual period due to impaired efficacy of the product.

What are the possible side effects of Neo-Penotran?​

Neo-Penotran is generally well tolerated. Vaginal irritation (eg: burning, itching) may occur after the first pessary is applied or towards the third day of the treatment due to the natural course of inflammation during vaginal infections. These symptoms are quickly reduced while the treatment continues. If there are severe irritation symptoms, stop the treatment immediately and seek medical advice. It is also common to find more vaginal discharge during the course of treatment.

What precautions should I take?

Neo-Penotran should not be used:

• In patients known to be hypersensitive to the active ingredients or their derivatives
• In patients using alcohol during the treatment or at least 3 days after the treatment
• In patients using disulfiram during the treatment or within 2 weeks
• During the first trimester of pregnancy
• In pregnant women who have trichomonal vaginitis in the first trimester
• In cases of porphyria, epilepsy and serious liver function disorders
• In virgins and in young patients who are not sexually mature

Always let your doctor know if you are pregnant or breastfeeding.

Neo-Penotran pessary must not be used with contraceptive diaphragms, condoms and other vaginal products (eg: tampons, douche or spermicide) concurrently during the treatment.

Handling and Storage

• ​Store in a cool and dry place, away from direct sunlight.
• Keep the medicine out of reach of children.
• Throw away all expired medicines.

The above information answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.

References

Neo-Penotran Patient Information Leaflet