Neo-Penotran Vaginal Pessary 14s

What is Metronidazole 500mg, Miconazole 100mg Pessary used for​​​?

This pessary is commonly used to treat various vaginal infections such as vaginal yeast infection (vaginal candidiasis), bacterial vaginosis (such as anaerobic vaginal infections and Gardnerella vaginalis), Trichomonas vaginalis and mixed vaginal infections. It contains two active ingredients - an antibiotic Metronidazole (500mg) and an antifungal Miconazole (100mg).

Dosage and How to Use​

This pessary is meant strictly for vaginal use. Your doctor may prescribe you one of the following regimens for your infection:

1. Insert one pessary deep into the vagina in the evening for 14 days or

2. Insert one pessary in the morning and one in the evening for 7 days.

In the case of recurrent vaginitis, option one (14 days regimen) should be used.

The pessary should be inserted deep into the vagina while in the lying position, and should not be used during the menstrual period due to impaired efficacy of the product.

What are the possible side effects of the Metronidazole 500mg,Miconazole 100mg Pessary?​

This medication is generally well tolerated. Vaginal irritation (eg: burning, itching) may occur after the first pessary is applied or towards the third day of the treatment due to the natural course of inflammation during vaginal infections. These symptoms are quickly reduced while the treatment continues. If there are severe irritation symptoms, stop the treatment immediately and seek medical advice. It is also common to find more vaginal discharge during the course of treatment.

What precautions should I take?

This medication should not be used:

• In patients known to be hypersensitive to the active ingredients or their derivatives
• In patients using alcohol during the treatment or at least 3 days after the treatment
• In patients using disulfiram during the treatment or within 2 weeks
• During the first trimester of pregnancy
• In pregnant women who have trichomonal vaginitis in the first trimester
• In cases of porphyria, epilepsy and serious liver function disorders
• In virgins and in young patients who are not sexually mature

Always let your doctor know if you are pregnant or breastfeeding.

This pessary must not be used with contraceptive diaphragms, condoms and other vaginal products (eg: tampons, douche or spermicide) concurrently during the treatment.

Handling and Storage

• ​Store in a cool and dry place, away from direct sunlight.
• Keep the medicine out of reach of children.
• Throw away all expired medicines.

The above information answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.