Yaz

What is this medication used for​​​?

Yaz® is a combined hormonal contraceptive that contains two types of female hormones, estrogen and progestogen. This medication can help prevent ovulation and regulates other naturally occurring hormones in the body. When taken correctly, this prevents pregnancy and promotes regular menstrual bleeding. 

Dosage and How to Use​

• Do not stop taking your medication without checking with your healthcare professional.
• If you are switching from other forms of contraception, please seek advice from your healthcare professional.
• You should take this medication after food.
• You may start taking this medication on the first or second day of your menses (if this is your first time taking hormonal contraceptives).
• If you are also using it for contraceptive purposes, a barrier method of contraception e.g. condoms, is recommended for the first 7 days of taking this medication for the first time.
• Each pack contains 24 pink (active) tablets and 4 white (inactive) tablets = 28 tablets.
• You should take one tablet daily for 28 days in a row, preferably at the same time every day. You must take the tablets in the correct sequence i.e. start each pack with the pink (active) tablets, followed by the white (inactive) tablets. 
• The next pack is started after the last tablet of the previous pack. Withdrawal bleeding (menses) usually starts on day 2 – 3 after the last white (inactive) tablet is taken and may not have finished before the next pack is started.

If you vomit or suffer from diarrhea within 3 to 4 hours of taking this medication, the tablet may not be absorbed. This is considered a missed dose. You should then follow the instructions above. 

What are the possible side effects of the medicines?​

• Spotting or bleeding may occur between your periods during the first few months of taking oral contraceptives. However, if this continues after the third month, check with your doctor. 
• Nausea, vomiting, bloating and stomach cramps - Take the medication after food to reduce these side effects 
• Breast tenderness
• Headache or migraine - You may take painkillers such as Paracetamol to manage headaches 
• Unable to tolerate contact lenses
• Weight changes, mood swings - Take medication at the same time every day to avoid huge changes in the hormone levels in your body
• Pigmentation of the skin - Apply sunblock when you are outdoors and avoid long hours of sun exposure

Inform your doctor if the side effects above become severe and bother you.

What are some rare but serious side-effects that I need to seek medical advice immediately?

The symptoms of a drug allergy include one or more of the following: 

• Swollen face/eyes/lips/tongue
• Difficulty in breathing
• Itchy skin rashes over your whole body

Using a combined hormonal medication increases a woman’s risk of developing blood clots compared to a woman not taking any combined hormonal contraception. The risk of developing a blood clot in a vein is highest during the first year a woman uses the medication. Other risk factors for developing blood clots include smoking and obesity. However, the formation of a blood clot is rare and the doctor would have considered the risks against the benefits before making the recommendation. 

The symptoms of a blood clot include one or more of the following:

• Any unusual sudden cough, breathlessness or difficulty in breathing 
• Severe pain in the chest which may reach the left arm
• Severe pain in legs or swelling in either of your legs
• Weakness or numbness in any part of your body
• Change in your speech, including slurring of words
• Change in your senses of hearing, smell or taste
• Vision changes such as loss of vision/blurred vision 

Other rare but serious effects that you may or may not experience: 

• Unusual, severe or long-lasting headache or worsening of migraine 
• Dizziness or fainting
  
• Severe pain in your abdomen
• Dark urine or light coloured stools
• Nausea and vomiting
• Loss of appetite
• Yellowing of eyes or skin

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

What precautions should I take?

Inform your healthcare professional if: 

• You are allergic to this medication or any of the other ingredients of this medication
• You are pregnant, planning to become pregnant, or breastfeeding 
• You are taking any other medications, including supplements, traditional medications and herbal remedies
• You have a history of or current medical conditions such as liver problems, stroke, clotting disorders, heart diseases, migraine headaches, epilepsy (fits), diabetes or cancer 
• You are a smoker 

What other medications and foods should I avoid when taking Yaz®?

Some medications including antibiotics and antifungals may affect how the medication works or be affected by the medication.  Please inform your other healthcare professionals about this medication that you are taking if you are seeing them for other medical conditions.

Handling and storage

• ​Keep your medicines in the original container or packaging, tightly closed or sealed in a cool and dry place, away from direct sunlight.
• Keep the medicine out of reach of children.
• Throw away all expired medicines.

The above information answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.

References

https://www.healthhub.sg/a-z/medications/444/Combined-Hormonal-Contraceptives-28-day-regimen