Aklief® (Trifarotene) Cream 0.005%

What is Aklief® 0.005% Cream used for​​​?

Aklief® 0.005% Cream contains the active ingredient trifarotene, which is a topical retinoid and a form of vitamin A. It is an innovative topical single agent retinoid cream proven safe and effective for acne on your face, shoulders, chest, and back. 

Trifarotene helps the skin replace its old skin cells at a faster speed, exfoliating away the old cells in the process and helps prevent new acne from forming. It can also reduce inflammatory acne often experienced with pimples.

How effective is Aklief® 0.005% Cream?

In clinical trials, people using Aklief® 0.005% Cream showed a significant reduction in facial acne lesions from as early as 2 weeks. However, individual results may vary. 

Clinical trial results also showed that Aklief® 0.005% Cream significantly reduced inflammatory facial and truncal (back) acne leisons by up to 57.4% after 12 weeks of usage.

Aklief® 0.005% Cream was designed to be more tolerable for patients with widespread acne (especially on the chest and back) or those who could not tolerate older generation retinoids such as Tretinoin.

Does Aklief® 0.005% Cream treat blackheads and whiteheads?

Aklief® 0.005% Cream can help reduce inflammatory acne and comedonal acne (more commonly known as blackheads and whiteheads).

Dosage and How to Use​

• Wash the skin with cleanser, then rinse and pat dry.
• Wash your hands before and after applying the medication.
• Apply a thin layer of medication to cover the affected areas in the evening or according to your doctor’s instructions.
• For your face, use 1 pump. For your upper back, shoulders, and chest, use 2 pumps. If needed, you may use an additional pump for your middle to lower back.
• Avoid applying the medication on broken skin or too near to your eyes, mouth and nose as it may cause irritation. 
• Flush the area thoroughly with water if the medication accidentally gets into your eyes, mouth, and nose.

What to do if I missed a dose?

If you forget to apply a dose of this medication, apply it as soon as you remember. Skip the dose if it is time for the next dose. Apply your next dose at the usual time. Do not apply two doses to make up for the missed dose.

What are the possible side effects of Aklief® 0.005% Cream?​

The most common side effects of Aklief 0.005% Cream include: application site irritation, itching, and sunburn.

Aklief 0.005% Cream may cause serious side effects, including: Local skin irritation. Local skin reactions are common with Aklief 0.005% Cream and are most likely to happen during the first 4 weeks of treatment and may decrease with continued use of Aklief 0.005% Cream.

Signs and symptoms of local skin reactions include:

• redness
• scaling
• dryness
• stinging or burning

To help reduce your risk of developing these local skin reactions, when you begin treatment with Aklief 0.005% Cream, you should begin applying a moisturizer on your skin as often as needed.
Tell your doctor if you develop symptoms of a local skin reaction. Your may be recommended to use Aklief 0.005% Cream less often, or to temporarily or permanently stop your treatment with Aklief 0.005% Cream.

Sometimes, your acne may seem to get worse during the first two to three weeks. This is a normal reaction. If you continue using this medicine, you will notice improvement. The best results may be achieved after four to seven weeks of treatment.

What precautions should I take?

Inform your healthcare professional if: 

• You are allergic to this medication or any of the other ingredients of this medication
• You are pregnant, planning to become pregnant, or breastfeeding

Avoid washing your face too often as this may increase the drying-out effect of your medication. Wash your face two to three times a day only.

Unless otherwise directed by your doctor, avoid using other “drying” preparations on the same treated areas to prevent severe irritations. These include harsh soaps and cleansers, alcoholic preparations and medicated cosmetics or soaps. 

Avoid staying directly under sunlight for long durations. Use a broad-spectrum sunscreen product with Sun Protection Factor (SPF) of at least 30 and wear protective clothing when you are exposed to direct sunlight.

Avoid applying heavy make-up and using oily cosmetics. It is recommended to choose make-up products with non-oily formulas.

Handling and storage

• Store in a cool dry place, away from direct sunlight.
• Keep out of sight and reach of children.

The above information answers some common questions about this medicine. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.

References

www.aklief.com